Salivary glucose as a non-invasive biomarker of type 2 diabetes mellitus
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Salivary glucose as a non-invasive biomarker of type 2 diabetes mellitus

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Salivary glucose as a non-invasive biomarker of type 2 diabetes mellitus

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dc.contributor.author Tiongco, Raphael-Enrique es
dc.contributor.author Bituin, Aira es
dc.contributor.author Arceo, Engracia es
dc.contributor.author Rivera, Nicole es
dc.contributor.author Singian, Eloisa es
dc.date.accessioned 2018-11-28T12:48:31Z
dc.date.available 2018-11-28T12:48:31Z
dc.date.issued 2018 es
dc.identifier.uri http://hdl.handle.net/10550/68128
dc.description.abstract Every year, millions of people are diagnosed with Diabetes mellitus (DM) and the number of new and undiagnosed cases continue to rise. Diagnosis of diabetes is usually performed by blood glucose analysis after fasting for a certain period. However, this method uses an invasive technique that can cause discomfort and even trauma to some patients which could eventually lead to behavioral changes such as avoidance of healthcare and laboratory testing. Studies that explore the diagnostic value of salivary glucose are promising due to the non-invasiveness of the test procedures and its potential correlation with blood results. The study conducted aimed to determine if salivary glucose can be utilized as an alternative to blood glucose in the screening, diagnosis, and monitoring of type 2 diabetes mellitus (T2DM). A total of 75 participants were recruited and equally divided into 3 groups (normal fasting glucose, impaired fasting glucose, and provisional DM) based on their fasting blood glucose (FBG) level. Blood and unstimulated saliva were collected from each participant and were subjected to glucose analysis using the routine glucose oxidase-peroxidase method. Using Pearson?s correlation and linear regression, a high degree and significant correlation was observed between blood and salivary glucose (r = 0.715, p<0.001). Further analysis showed that salivary glucose is 88.5% sensitive and 61.5% specific with a positive predictive value of 45.8%, and a negative predictive value of 97.1%. Salivary glucose is comparable to blood glucose in diagnosing and monitoring T2DM and is considered more advantageous than blood due to its non-invasive nature. es
dc.source Tiongco, Raphael-Enrique ; Bituin, Aira ; Arceo, Engracia ; Rivera, Nicole ; Singian, Eloisa. Salivary glucose as a non-invasive biomarker of type 2 diabetes mellitus. En: Journal of Clinical and Experimental Dentistry, 10 9 2018: 902-907 es
dc.title Salivary glucose as a non-invasive biomarker of type 2 diabetes mellitus es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.55009 es

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