Activation of bee venom phospholipase A2 through a peptide-enzyme complex
NAGIOS: RODERIC FUNCIONANDO

Activation of bee venom phospholipase A2 through a peptide-enzyme complex

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Activation of bee venom phospholipase A2 through a peptide-enzyme complex

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dc.contributor.author Mingarro Muñoz, Ismael
dc.contributor.author Pérez Payá, Enrique
dc.contributor.author Pinilla, Clemencia
dc.contributor.author Appel, Jon R.
dc.contributor.author Houghten, Richard A.
dc.contributor.author Blondelle, Sylvie E.
dc.date.accessioned 2018-04-13T14:44:30Z
dc.date.available 2018-04-13T14:44:30Z
dc.date.issued 1995
dc.identifier.uri http://hdl.handle.net/10550/65665
dc.description.abstract Phospholipase A2 activation by membrane‐bound peptides was investigated in order to understand the role of the membrane‐induced conformation on activation, and to examine the occurrence of a peptide‐enzyme complex at the lipid/water interface. For the peptides studies, bee venom phospholipase A2 was stimulated regardless of the membrane‐bound conformation (α‐helix, β‐sheet or random coil). Using antisera raised against melittin, we were able to demonstrate the occurrence of a calcium‐dependent complex involving the enzyme, phospholipid substrate, and peptide.
dc.language.iso eng
dc.relation.ispartof Febs Letters, 1995, vol. 372, num. 1, p. 131-134
dc.rights.uri info:eu-repo/semantics/openAccess
dc.source Mingarro Muñoz, Ismael Pérez Payá, Enrique Pinilla, Clemencia Appel, Jon R. Houghten, Richard A. Blondelle, Sylvie E. 1995 Activation of bee venom phospholipase A2 through a peptide-enzyme complex Febs Letters 372 1 131 134
dc.subject Pèptids
dc.subject Abelles
dc.title Activation of bee venom phospholipase A2 through a peptide-enzyme complex
dc.type info:eu-repo/semantics/article
dc.date.updated 2018-04-13T14:44:30Z
dc.identifier.doi https://doi.org/10.1016/0014-5793(95)00964-B
dc.identifier.idgrec 008447

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