Giant cell angiofibroma of the oral cavity : a case report and review of the literature
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Giant cell angiofibroma of the oral cavity : a case report and review of the literature

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Giant cell angiofibroma of the oral cavity : a case report and review of the literature

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Andrade, Cleverton Roberto de; Lopes, Márcio Ajudarte; Almeida, Oslei Paes de; León, Jorge Esquiche; Mistro, Florence; Kignel, Sergio
Aquest document és un/a article publicat, creat/da en: 2008
Giant cell angiofibroma is a well-circumscribed, normally encapsulated, distinctive orbital soft tissue tumor. However, it is now recognized that this lesion can also present in other locations, including the oral cavity. The morphological hallmark is a richly vascularized, patternless spindle cell proliferation containing pseudovascular spaces and floret-type multinucleate giant cells. CD34 immunoreactivity, although not specific, represents the only immunohistochemical finding of potential diagnostic value. We present a case of a 44-year-old male Caucasian patient complaining of painless solitary nodule arising on the right buccal mucosa, which was diagnosed as giant cell angiofibroma. To the best of our knowledge, this is the third case of oral giant cell angiofibroma reported in the English-language literature.

    Andrade, Cleverton Roberto de ; Lopes, Márcio Ajudarte ; Almeida, Oslei Paes de ; León, Jorge Esquiche ; Mistro, Florence ; Kignel, Sergio. Giant cell angiofibroma of the oral cavity : a case report and review of the literature. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 13 9 2008: 2-
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