Epstein-Barr virus in oral proliferative verrucous leukoplakia and squamous cell carcinoma : a preliminary study
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Epstein-Barr virus in oral proliferative verrucous leukoplakia and squamous cell carcinoma : a preliminary study

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Epstein-Barr virus in oral proliferative verrucous leukoplakia and squamous cell carcinoma : a preliminary study

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Bagán Sebastián, José Vicente Perfil; Jiménez Soriano, Yolanda; Murillo Cortés, Judith; Poveda Roda, Rafael; Díaz Fernández, José María; Gavaldá Esteve, Carmen; Margaix Muñoz, María; Scully, Crispian; Alberola, Trinidad M.; Torres Puente, Manuela; Pérez Alonso, Manuel
Aquest document és un/a article publicat, creat/da en: 2008
The aim of this study was to analyze proliferative verrucous leukoplakia (PVL) and oral squamous cell carcinoma (OSCC) for the possible presence of Epstein-Barr virus (EBV). We studied three groups: Sub-Group 1 was composed of 10 patients with PVL, (6 of whom had developed OSCC); Sub-Group 2 comprised 5 patients with OSCC but no preceding PVL; and Sub-Group 3 were 5 controls with clinically normal oral mucosa. Oral biopsies from all cases were examined for Epstein-Barr virus (EBV) by nested PCR. EBV was detected in 60% of Sub-Group 1 patients (PVL ) and in 40% of Sub-Group 2 (OSCC), but in 0% of SubGroup 3 (controls).

    Bagán Sebastián, José Vicente ; Jiménez Soriano, Yolanda ; Murillo Cortés, Judith ; Poveda Roda, Rafael ; Díaz Fernández, José María ; Gavaldá Esteve, Carmen ; Margaix Muñoz, María ; Scully, Crispian ; Alberola, Trinidad M. ; Torres Puente, Manuela ; Pérez Alonso, Manuel. Epstein-Barr virus in oral proliferative verrucous leukoplakia and squamous cell carcinoma : a preliminary study. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 13 2 2008: 5-
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