Host defence mechanisms against bacterial aggression in periodontal disease : basic mechanisms
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Host defence mechanisms against bacterial aggression in periodontal disease : basic mechanisms

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Host defence mechanisms against bacterial aggression in periodontal disease : basic mechanisms

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Bascones Martínez, Antonio; Muñoz Corcuera, Marta; Noronha, Susana; Mota, Paula; Bascones Ilundain, Cristina; Campo Trapero, Julián
This document is a artículo publicadoDate2009

Este documento está disponible también en : http://hdl.handle.net/10550/60640
Periodontal diseases are complex bacteria-induced infections characterised by an inflammatory host response to plaque microbiota and their by-products. Most of these microorganisms have virulence factors capable of causing massive tissue destruction both directly, through tissue invasion and the production of harmful substances, or indirectly, by activation of host defense mechanisms, creating an inflammatory infiltrate of potent catabolic activity that can interfere with normal host defense mechanisms. In response to the aggression, host defense mechanisms activate innate and adaptive immune responses. Our aim is to offer a general overview of the main mechanisms involved in the host response to bacterial aggression in periodontitis, such as lipopolysaccharide receptor CD14, complement system, polymorphonuclear neutrophils, antibodies and immunoglobulins.

    Bascones Martínez, Antonio ; Muñoz Corcuera, Marta ; Noronha, Susana ; Mota, Paula ; Bascones Ilundain, Cristina ; Campo Trapero, Julián. Host defence mechanisms against bacterial aggression in periodontal disease : basic mechanisms. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 14 12 2009: 13-

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