Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS)
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Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS)

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Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS)

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dc.contributor.author Busamia, Beatriz E. es
dc.contributor.author González Moles, M.A. es
dc.contributor.author Mazzeo, Marcelo-Adrián es
dc.contributor.author Linares, Jorge-Alberto es
dc.contributor.author Demarchi, Marcela es
dc.contributor.author Gobbi, Carla es
dc.contributor.author Albiero, Eduardo es
dc.contributor.author Finkelberg, Ana-Beatriz es
dc.date.accessioned 2017-07-27T07:25:47Z
dc.date.available 2017-07-27T07:25:47Z
dc.date.issued 2010 es
dc.identifier.uri http://hdl.handle.net/10550/60337
dc.description.abstract The aim of this study was to assess changes in salivary electrolyte flow and composition and the presence of anti-Ro/SSA and anti-La/SSB serum and saliva antibodies and their implications for the non-invasive diagnosis of SS. Study design: 73 patients were studied, divided into the following experimental groups: primary Sjögren syndrome (SSp) (n=15), secondary SS (SSs) (n=17), dry mouth, dry eye without Sjögren?s syndrome (BO) (n=20) and healthy controls (C) (n=21). We conducted a baseline assessment of salivary flow and saliva sampling for the measurement of sodium, chlorine, potassium, calcium and phosphate electrolytes, and the determination of antiRo/SSA and La/SSB antibodies; a serum sampling was made to assess antibody positivity. Results: Salivary flow in SSp, SSs and BO was significantly lower (p<0.001) relative to C. The salivary composition of SS showed an increase of inorganic components. Anti-Ro/SSA and anti-La/SSB antibodies occurred more frequently in serum and saliva in SS patients compared with BO and C, with higher frequency of positivity in serum compared with saliva. Conclusion: Our results suggest new tools that could aid the non-traumatic diagnosis of the origin of hyposalivation es
dc.source Busamia, Beatriz E. ; González Moles, M.A. ; Mazzeo, Marcelo-Adrián ; Linares, Jorge-Alberto ; Demarchi, Marcela ; Gobbi, Carla ; Albiero, Eduardo ; Finkelberg, Ana-Beatriz. Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS). En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 15 3 2010: 4- es
dc.title Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS) es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.15.e437 es

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