Effect of low-calcium diet and grind diet on bone turnover of ovariectomized female rats
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Effect of low-calcium diet and grind diet on bone turnover of ovariectomized female rats

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Effect of low-calcium diet and grind diet on bone turnover of ovariectomized female rats

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dc.contributor.author Costa, Giselly Parizoto es
dc.contributor.author Leite, Deise Silva es
dc.contributor.author Prado, Renata Falchete do es
dc.contributor.author Silveira, Vanessa Ávila Sarmento es
dc.contributor.author Carvalho, Yasmin Rodarte es
dc.date.accessioned 2017-07-26T11:20:30Z
dc.date.available 2017-07-26T11:20:30Z
dc.date.issued 2011 es
dc.identifier.uri http://hdl.handle.net/10550/60124
dc.description.abstract Objective: The variety of methodologies used to investigate ovariectomized female rats shows different results, which makes a clinical application of these results difficult. The purpose of this work was to evaluate the effect of masticatory effort reduction and of low-calcium diet on maxillary bone turnover of ovariectomized female rats. Study Design: Eighty-four female rats were divided into four groups of 21 animals each as follows: SHAM - sham-operated; OVZ - ovariectomized and fed a standard commercial diet; LCD - fed a low calcium diet, and GCD - fed a grind commercial diet. The inferior first molars were extracted bilaterally 15 days after the ovariectomy, and the animals were euthanized 3, 5 and 8 weeks after ovaries removal. The maxillae were embedded in methylmetacrilate. The results were submitted to analysis of variance. Results: The daily mineral apposition rate lowered with time and was not different between SHAM and OVZ groups. The trabecular bone volume of SHAM and OVZ animals was similar and decreased with time. The GCD animals presented the lowest means and the LCD the highest in comparison to the OVZ group. Conclusion: It was concluded that ovariectomy and a low calcium diet did not cause significant maxillary bone loss in the first molar region, and even in the absence of the antagonist tooth, they did not cause maxillary bone turnover. The grind commercial diet is a good alternative for the study of maxillary bone loss in ovariectomized female rats. © Medicina Oral S. L. es
dc.source Costa, Giselly Parizoto ; Leite, Deise Silva ; Prado, Renata Falchete do ; Silveira, Vanessa Ávila Sarmento ; Carvalho, Yasmin Rodarte. Effect of low-calcium diet and grind diet on bone turnover of ovariectomized female rats. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 16 4 2011: 7- es
dc.title Effect of low-calcium diet and grind diet on bone turnover of ovariectomized female rats es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.16.e497 es

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