Highly enantioselective copper(I)-catalyzed conjugate addition of 1,3-diynes to α,β-unsaturated trifluoromethyl ketones
NAGIOS: RODERIC FUNCIONANDO

Highly enantioselective copper(I)-catalyzed conjugate addition of 1,3-diynes to α,β-unsaturated trifluoromethyl ketones

Repositori DSpace/Manakin

Highly enantioselective copper(I)-catalyzed conjugate addition of 1,3-diynes to α,β-unsaturated trifluoromethyl ketones

Mostra el registre complet de l'element

Visualització       (1.427Mb)

Exportar a Refworks
    
Sanz Marco, Amparo; Blay Llinares, Gonzalo; Muñoz, M. Carmen; Pedro, José Ramón
Aquest document és un/a article, creat/da en: 2015
The conjugate diynylation of a,b-unsaturated trifluoromethyl ketones is carried out in the presence of a low catalytic load (2.5 mol%) of a copper(I)-MeOBIPHEP complex, triethylamine and a terminal 1,3-diyne. Pre-metalation of the terminal 1,3-diyne with stoichiometric or higher amounts of dialkylzinc reagent is not required. The corresponding internal diynes bearing a propargylic stereogenic center are obtained with good yields and excellent enantioselectivities.

    Sanz Marco, Amparo Blay Llinares, Gonzalo Muñoz, M. Carmen Pedro, José Ramón 2015 Highly enantioselective copper(I)-catalyzed conjugate addition of 1,3-diynes to α,β-unsaturated trifluoromethyl ketones Chemical Communications 51 8958 8961
http://dx.doi.org/10.1039/c5cc01676b
distribuït sota llicència Creative Commons de Reconeixement-NoComercial 3.0 No adaptada

Aquest element apareix en la col·lecció o col·leccions següent(s)

Mostra el registre complet de l'element

Cerca a RODERIC

Cerca avançada

Visualitza

Estadístiques