Treatment of oral mucositis due to chemotherapy
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Treatment of oral mucositis due to chemotherapy

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Treatment of oral mucositis due to chemotherapy

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dc.contributor.author Chaveli López, Begonya es
dc.contributor.author Bagán Sebastián, José Vicente es
dc.date.accessioned 2016-05-26T09:33:03Z
dc.date.available 2016-05-26T09:33:03Z
dc.date.issued 2016 es
dc.identifier.uri http://hdl.handle.net/10550/53793
dc.source Chaveli López, Begonya ; Bagán Sebastián, José Vicente. Treatment of oral mucositis due to chemotherapy. En: Journal of Clinical and Experimental Dentistry, 2016, Vol. 8, No. 2: 201-209 es
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Treatment of oral mucositis due to chemotherapy es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.description.abstractenglish Introduction: The management of oral mucositis is a challenge, due to its complex biological nature. Over the last 10 years, different strategies have been developed for the management of oral mucositis caused by chemotherapy in cancer patients. Material and Methods: An exhaustive search was made of the PubMed-Medline, Cochrane Library and Scopus databases, crossing the key words “oral mucositis”, “prevention” and “treatment” with the terms “chemotherapy” and “radiotherapy” by means of the boolean operators “AND” and “NOT”. A total of 268 articles were obtained, of which 96 met the inclusion criteria. Results: Several interventions for the prevention of oral mucositis, such as oral hygiene protocols, amifostine, benzidamine, calcium phosphate, cryotherapy and iseganan, among others, were found to yield only limited benefits. Other studies have reported a decrease in the appearance and severity of mucositis with the use of cytoprotectors (sucralfate, oral glutamine, hyaluronic acid), growth factors, topical polyvinylpyrrolidone, and low power laser irradiation. Conclusions: Very few interventions of confirmed efficacy are available for the management of oral mucositis due to chemotherapy. However, according to the reviewed literature, the use of palifermin, cryotherapy and low power laser offers benefits, reducing the incidence and severity of oral mucositis – though further studies are needed to confirm the results obtained. es

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