Melatonin enhances vertical bone augmentation in rat calvaria secluded spaces
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Melatonin enhances vertical bone augmentation in rat calvaria secluded spaces

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Melatonin enhances vertical bone augmentation in rat calvaria secluded spaces

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dc.contributor.author Shino, Hiromichi es
dc.contributor.author Hasuike, Akira es
dc.contributor.author Arai, Yoshinori es
dc.contributor.author Honda, Masaki es
dc.contributor.author Isokawa, Keitaro es
dc.contributor.author Sato, Shuichi es
dc.date.accessioned 2016-04-06T12:31:12Z
dc.date.available 2016-04-06T12:31:12Z
dc.date.issued 2016 es
dc.identifier.uri http://hdl.handle.net/10550/52010
dc.relation es
dc.source Shino, Hiromichi ; Hasuike, Akira ; Arai, Yoshinori ; Honda, Masaki ; Isokawa, Keitaro ; Sato, Shuichi. Melatonin enhances vertical bone augmentation in rat calvaria secluded spaces. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2016, Vol. 21, No. 1: 122- es
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Melatonin enhances vertical bone augmentation in rat calvaria secluded spaces es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.description.abstractenglish Background: Melatonin has many roles, including bone remodeling and osseointegration of dental implants. The topical application of melatonin facilitated bone regeneration in bone defects. We evaluated the effects of topical application of melatonin on vertical bone augmentation in rat calvaria secluded spaces. Material and Methods: In total, 12 male Fischer rats were used and two plastic caps were fixed in the calvarium. One plastic cap was filled with melatonin powder and the other was left empty. Results: Newly generated bone at bone defects and within the plastic caps was evaluated using micro-CT and histological sections. New bone regeneration within the plastic cap was increased significantly in the melatonin versus the control group. Conclusions: Melatonin promoted vertical bone regeneration in rat calvaria in the secluded space within the plastic cap. es

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