Evaluation of Xerostomia and salivary flow rate in Hashimoto’s Thyroiditis
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Evaluation of Xerostomia and salivary flow rate in Hashimoto’s Thyroiditis

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Evaluation of Xerostomia and salivary flow rate in Hashimoto’s Thyroiditis

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dc.contributor.author Agha-Hosseini, Farzaneh es
dc.contributor.author Shirzad, Nooshin es
dc.contributor.author Moosavi, Mahdieh Sadat es
dc.date.accessioned 2016-04-06T12:31:10Z
dc.date.available 2016-04-06T12:31:10Z
dc.date.issued 2016 es
dc.identifier.uri http://hdl.handle.net/10550/52006
dc.relation es
dc.source Agha-Hosseini, Farzaneh ; Shirzad, Nooshin ; Moosavi, Mahdieh Sadat. Evaluation of Xerostomia and salivary flow rate in Hashimoto’s Thyroiditis. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2016, Vol. 21, No. 1: 1- es
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Evaluation of Xerostomia and salivary flow rate in Hashimoto’s Thyroiditis es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.description.abstractenglish Background: One of the most common causes of hypothyroidism is Hashimoto´s Thyroiditis (HT). Early detection of dry mouth is critical in preserving and promoting systemic and oral health. In this study we have assessed, for the first time, salivary function and xerostomia in HT patients who have not been involved with Sjögren´s syndrome. Material and Methods: HT was diagnosed in 40 patients based on clinical findings and positive anti-thyroid peroxidase antibodies (anti-TPO). Controls, matched by sex, age and body mass index (BMI), and with no history of thyroid disease, were selected. A questionnaire was used for diagnosis of xerostomia. Saliva samples were taken between 8 a.m. and 9 a.m., and at least 2 hours after the last intake of food or drink. The flow rate was calculated in milliliters per minute. Results: Xerostomia was significantly higher in patients with HT. Unstimulated salivary flow rate was significantly lower in the HT group. Stimulated salivary flow rate was lower in HT group, but the difference was not significant. Conclusions: The patients with HT experienced xerostomia, and their salivary flow rate was diminished. Spitting the saliva then assessing salivary flow rate based on milliliter per minute is non-invasive, fast, and simple for chair-side diagnosis of dry mouth. Autoimmune diseases can be accompanied by salivary gland dysfunction. This may be due to the effect of cytokines in the autoimmune process or because of thyroid hormone dysfunctions es

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