Cytotoxicity of glass ionomer cements containing silver nanoparticles

Cytotoxicity of glass ionomer cements containing silver nanoparticles

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Cytotoxicity of glass ionomer cements containing silver nanoparticles

Show simple item record Siqueira, Patrícia Correia es Magalhães, Ana Paula Rodrigues es Pires, Wanessa Carvalho es Pereira, Flávia Castro es Silveira Lacerda, Elisângela Paula es Carrião, Marcus Santos es Bakuzis, Andris Figueiroa es Souza Costa, Carlos Alberto es Lopes, Lawrence Gonzaga es Estrela, Carlos es 2016-01-20T12:12:21Z 2016-01-20T12:12:21Z 2015 es
dc.source Siqueira, Patrícia Correia ; Magalhães, Ana Paula Rodrigues ; Pires, Wanessa Carvalho ; Pereira, Flávia Castro ; Silveira Lacerda, Elisângela Paula ; Carrião, Marcus Santos ; Bakuzis, Andris Figueiroa ; Souza Costa, Carlos Alberto ; Lopes, Lawrence Gonzaga ; Estrela, Carlos. Cytotoxicity of glass ionomer cements containing silver nanoparticles. En: Journal of Clinical and Experimental Dentistry, 2015, Vol. 7, No. 5: 622-627 es
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Cytotoxicity of glass ionomer cements containing silver nanoparticles es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.description.abstractenglish Background: Some studies have investigated the possibility of incorporating silver nanoparticles (NAg) into dental materials to improve their antibacterial properties. However, the potential toxic effect of this material on pulp cells should be investigated in order to avoid additional damage to the pulp tissue. This study evaluated the cytotoxicity of conventional and resin-modified glass ionomer cements (GIC) with and without addition of NAg. Material and Methods: NAg were added to the materials at two different concentrations by weight: 0.1% and 0.2%. Specimens with standardized dimensions were prepared, immersed in 400 μL of culture medium and incubated at 37°C and 5% CO2 for 48 h to prepare GIC liquid extracts, which were then incubated in contact with cells for 48 h. Culture medium and 0.78% NAg solution were used as negative and positive controls, respectively. Cell viability was determined by MTT and Trypan Blue assays. ANOVA and the Tukey test (α=0.05) were used for statistical analyses. Results: Both tests revealed a significant decrease in cell viability in all groups of resin modified cements ( p ˂0.001). There were no statistically significant differences between groups with and without NAg ( p ˃0.05). The differences in cell viability between any group of conventional GIC and the negativ e control were not statistically significant ( p >0.05). Conclusions: NAg did not affect the cytotoxicity of the GIC under evaluation es

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