Jaw mobility changes in patients with upper aerodigestive tract cancer undergoing radiation therapy
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Jaw mobility changes in patients with upper aerodigestive tract cancer undergoing radiation therapy

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Jaw mobility changes in patients with upper aerodigestive tract cancer undergoing radiation therapy

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dc.contributor.author Bragante, Karoline es
dc.contributor.author Wienandts, Patrícia es
dc.contributor.author Mozzini, Carolina es
dc.contributor.author Pinto, Rosélie es
dc.contributor.author da Motta, Neiro es
dc.contributor.author Jotz, Geraldo es
dc.date.accessioned 2016-01-20T11:01:36Z
dc.date.available 2016-01-20T11:01:36Z
dc.date.issued 2015 es
dc.identifier.uri http://hdl.handle.net/10550/50137
dc.description.abstract Background: Radiation therapy is a therapeutic modality widely used for treatment of upper aerodigestive tract (UADT) neoplasms. However, its action is not restricted to tumor cells, and it may cause a variety of adverse reactions, including reduced jaw mobility. Material and Methods: A prospective cohort study was conducted to assess changes in jaw mobility in patients with UADT cancer undergoing radiation therapy. Results: Fifty-six patients completed the study. The results showed a significant reduction in mouth opening ( p <0.001), right lateral excursion ( p =0.038) and left lateral excursion ( p =0.035) of the jaw, a significant increase in the presence ( p <0.001) and severity of oral mucositis ( p <0.001), and a significant decrease in performance status ( p <0.001) after radiation therapy. Thirty-six patients (64.3%) exhibited reduction in mouth opening after treatment. The variables significantly associated with mouth opening reduction on bivariate analysis were: modification of diet ( p =0.037), radiation field ( p =0.024), presence of mucositis ( p =0.003), and reduction in performance status ( p =0.007). After adjustment by the multivariate model, the only variables that remained significantly associated with reduction in mouth opening were presence of mucositis ( p =0.018) and reduction in performance status ( p =0.47). Conclusions: These findings indicate that patients with upper aerodigestive tract cancer experience reduced jaw mobility after radiation therapy, which is strongly correlated with mucositis and reduced functional ability. es
dc.relation http://dialnet.unirioja.es/servlet/citart?info=link&codigo=5277072&orden=0 es
dc.source Bragante, Karoline ; Wienandts, Patrícia ; Mozzini, Carolina ; Pinto, Rosélie ; da Motta, Neiro ; Jotz, Geraldo. Jaw mobility changes in patients with upper aerodigestive tract cancer undergoing radiation therapy. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2015, Vol. 20, No. 6: 1- es
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Jaw mobility changes in patients with upper aerodigestive tract cancer undergoing radiation therapy es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es

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