Sociodemographic Factors and Clinical Conditions Associated to Hospitalization in Influenza A (H1N1) 2009 Virus Infected Patients in Spain, 2009–2010
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Sociodemographic Factors and Clinical Conditions Associated to Hospitalization in Influenza A (H1N1) 2009 Virus Infected Patients in Spain, 2009–2010

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Sociodemographic Factors and Clinical Conditions Associated to Hospitalization in Influenza A (H1N1) 2009 Virus Infected Patients in Spain, 2009–2010

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dc.contributor.author González Candelas, Fernando es_ES
dc.contributor.author Astray, Jenaro es_ES
dc.contributor.author Alonso, Jordi es_ES
dc.contributor.author Castro, Ady es_ES
dc.contributor.author Cantón, Rafael es_ES
dc.contributor.author Galán, Juan Carlos es_ES
dc.contributor.author Garin, Olatz es_ES
dc.contributor.author Sáez, Marc es_ES
dc.contributor.author Soldevila, Nuria es_ES
dc.contributor.author Baricot, Maretva es_ES
dc.contributor.author Castilla, Jesús es_ES
dc.contributor.author Godoy, Pere es_ES
dc.contributor.author Delgado-Rodríguez, Miguel es_ES
dc.contributor.author Martín, Vicente es_ES
dc.contributor.author Mayoral, José María es_ES
dc.contributor.author Pumarola, Tomás es_ES
dc.contributor.author Quintana, José María es_ES
dc.contributor.author Tamames, Sonia es_ES
dc.contributor.author Domínguez, Ángela es_ES
dc.date.accessioned 2015-06-19T10:19:53Z
dc.date.available 2015-06-19T10:19:53Z
dc.date.issued 2012 es_ES
dc.identifier.uri http://hdl.handle.net/10550/44556
dc.description.abstract The emergence and pandemic spread of a new strain of influenza A (H1N1) virus in 2009 resulted in a serious alarm in clinical and public health services all over the world. One distinguishing feature of this new influenza pandemic was the different profile of hospitalized patients compared to those from traditional seasonal influenza infections. Our goal was to analyze sociodemographic and clinical factors associated to hospitalization following infection by influenza A(H1N1) virus. We report the results of a Spanish nationwide study with laboratory confirmed infection by the new pandemic virus in a case-control design based on hospitalized patients. The main risk factors for hospitalization of influenza A (H1N1) 2009 were determined to be obesity (BMI≥40, with an odds-ratio [OR] 14.27), hematological neoplasia (OR 10.71), chronic heart disease, COPD (OR 5.16) and neurological disease, among the clinical conditions, whereas low education level and some ethnic backgrounds (Gypsies and Amerinds) were the sociodemographic variables found associated to hospitalization. The presence of any clinical condition of moderate risk almost triples the risk of hospitalization (OR 2.88) and high risk conditions raise this value markedly (OR 6.43). The risk of hospitalization increased proportionally when for two (OR 2.08) or for three or more (OR 4.86) risk factors were simultaneously present in the same patient. These findings should be considered when a new influenza virus appears in the human population. es_ES
dc.source PLoS ONE Vol. 7 Issue 3: es_ES
dc.title Sociodemographic Factors and Clinical Conditions Associated to Hospitalization in Influenza A (H1N1) 2009 Virus Infected Patients in Spain, 2009–2010 es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.identifier.doi 10.1371/journal.pone.0033139 es_ES
dc.identifier.idgrec 084748 es_ES

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