A low cortisol response to acute stress is related to worse basal memory performance in older people
NAGIOS: RODERIC FUNCIONANDO

A low cortisol response to acute stress is related to worse basal memory performance in older people

DSpace Repository

A low cortisol response to acute stress is related to worse basal memory performance in older people

Show simple item record

dc.contributor.author Almela Zamorano, Mercedes es_ES
dc.contributor.author Hidalgo Calvo, Vanesa es_ES
dc.contributor.author van der Meij, Leander es_ES
dc.contributor.author Pulópulos Tripiana, Matías Miguel es_ES
dc.contributor.author Villada Rodríguez, Carolina es_ES
dc.contributor.author Salvador Fernández-Montejo, Alicia es_ES
dc.date.accessioned 2015-06-10T08:38:57Z
dc.date.available 2015-06-10T08:38:57Z
dc.date.issued 2014
dc.identifier.uri http://hdl.handle.net/10550/44281
dc.description.abstract Age-related memory decline has been associated with a faulty regulation of the hypothalamus-pituitary-adrenal axis (HPA-axis). The aim of this study was to investigate whether the magnitude of the stress-induced cortisol increase is related to memory performance when memory is measured in non-stressful conditions. To do so, declarative and working memory performance were measured in 31 men and 35 women between 55 and 77 years of age. On a different day, the magnitude of their cortisol response to acute psychosocial stress was measured. The relationship between the cortisol response and memory performance was U shaped: a low cortisol response to stress was related to poorer declarative and working memory performance, whereas those who did not increase their cortisol levels and those who had the largest cortisol increase had better declarative and working memory capabilities. Sex did not moderate these relationships. These results suggest that a low cortisol response to stress could reflect a defective HPA-axis response to stressors that is accompanied by poorer memory performance. Conversely, a high cortisol response seems to reflect a correct functioning of the HPA-axis and may protect against memory deficits in the later stages of human life. es_ES
dc.source Frontiers in Aging Neuroscience Vol. 6 es_ES
dc.subject cortisol es_ES
dc.subject declarative memory es_ES
dc.subject working memory es_ES
dc.subject HPA-axis es_ES
dc.subject elderly es_ES
dc.subject older people es_ES
dc.subject middle-age es_ES
dc.subject acute psychosocial stress es_ES
dc.title A low cortisol response to acute stress is related to worse basal memory performance in older people es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.identifier.doi 10.3389/fnagi.2014.00157 es_ES
dc.identifier.idgrec 099335 es_ES

View       (837.4Kb)

This item appears in the following Collection(s)

Show simple item record

Search DSpace

Advanced Search

Browse

Statistics