Prospective double-blind clinical trial evaluating the effectiveness of Bromelain in the third molar extraction postoperative period
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Prospective double-blind clinical trial evaluating the effectiveness of Bromelain in the third molar extraction postoperative period

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Prospective double-blind clinical trial evaluating the effectiveness of Bromelain in the third molar extraction postoperative period

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dc.contributor.author Barrera Núñez, María del Carmen de la es
dc.contributor.author Yáñez Vico, Rosa María es
dc.contributor.author Batista Cruzado, Antonio es
dc.contributor.author Heurtebise Saavedra, Jean Michel es
dc.contributor.author Castillo de Oyagüe, Raquel es
dc.contributor.author Torres Lagares, Daniel es
dc.date.accessioned 2014-07-04T07:54:33Z
dc.date.available 2014-07-04T07:54:33Z
dc.date.issued 2014 es
dc.identifier.uri http://hdl.handle.net/10550/36859
dc.relation http://www.medicinaoral.com/pubmed/medoralv19_i2_p157.pdf es
dc.source Barrera Núñez, María del Carmen de la ; Yáñez Vico, Rosa María ; Batista Cruzado, Antonio ; Heurtebise Saavedra, Jean Michel ; Castillo de Oyagüe, Raquel ; Torres Lagares, Daniel. Prospective double-blind clinical trial evaluating the effectiveness of Bromelain in the third molar extraction postoperative period. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2014, Vol. 19, No. 2: 157-162 es
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Prospective double-blind clinical trial evaluating the effectiveness of Bromelain in the third molar extraction postoperative period es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.description.abstractenglish Objectives: To evaluate the anti-inflammatory and analgesic effect of Bromelain (pineapple extract) administered orally in the postoperative after extraction of impacted lower molars. Study Design: This is a prospective, placebo-controlled, unicentric, double-blind study; the sample size was 34 patients. The pre and postoperative outcomes, evaluated on the third (D3) and eighth day (D8), included inflam - tion, pain and oral aperture, as well as the need for analgesics. One group received bromelain 150mg per day for three days and 100mg on days 4 to 7. The other group received placebo in the same dosage. All outcomes wer - recorded quantitatively and analyzed with the Mann-Whitney U test for independent samples. Results: Although there were no statistically significant differences between the treatment groups, a trend towards less inflammation and improved oral aperture was observed in the group that received bromelain, compared to the group that received placebo. This trend can be attributed completely to random reasons, since there is no statistical difference in the results. Conclusions: Further studies are necessary to analyze different administration patterns and doses of bromelain for the use in the postoperative of impacted third molars. es

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