Treatment of cervicofacial actinomycosis: a report of 19 cases and review of literature
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Treatment of cervicofacial actinomycosis: a report of 19 cases and review of literature

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Treatment of cervicofacial actinomycosis: a report of 19 cases and review of literature

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dc.contributor.author Moghimi, Meshkan es
dc.contributor.author Salentijn, Erik es
dc.contributor.author Debets Ossenkop, Yvette es
dc.contributor.author Karagozoglu, Kemal H. es
dc.contributor.author Forouzanfar, Tymour es
dc.date.accessioned 2014-05-29T07:11:37Z
dc.date.available 2014-05-29T07:11:37Z
dc.date.issued 2013 es
dc.identifier.uri http://hdl.handle.net/10550/35659
dc.source Moghimi, Meshkan ; Salentijn, Erik ; Debets Ossenkop, Yvette ; Karagozoglu, K.H. ; Forouzanfar, Tymour. Treatment of cervicofacial actinomycosis: a report of 19 cases and review of literature. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2013, Vol. 18, No. 4: 627-632 es
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Treatment of cervicofacial actinomycosis: a report of 19 cases and review of literature es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.description.abstractenglish Objectives: Actinomycosis is a chronic suppurative granulomatous infection caused by the Actinomyces genus. Orocervicofacial actinomycosis is the most common form of the disease, seen in up to 55% of cases. All forms of actinomycosis are treated with high doses of intravenous penicillin G over two to six weeks, followed by oral penicillin V. Large studies on cervicofacial actinomycosis are lacking. Therefore proper guidelines for treatment and treatment duration are difficult to establish. The aim of this study is to establish effective treatment and treatment duration for orocervicofacial actinomycosis. Study design: A Pubmed and Embase search was performed with the focus on treatment and treatment duration for cervicofacial actinomycosis. The hospital records of all patients presenting to our department with head and neck infection from January 2000 to December 2010 were reviewed, retrospectively. The following data were collected: age, gender, clinical presentation, aetiology, duration of symptoms, microbiological findings, treatment, and duration of treatment. The treatment and treatment duration is subsequently compared to the literature. Results: The literature search provided 12 studies meeting the inclusion criteria. All studies were retrospective in nature. Penicillin or amoxicillin/clavulanic acid are the preferred antibiotic regimens found in the literature. Most of our patients were treated with a combination of penicillin G 12 million units/day and metronidazol 500 mg 3/ day, most commonly for a duration of 1 - 4 weeks, being shorter than the 3 - 52 weeks reported in the literature. Conclusion: When actinomycosis is suspected, our review has shown that a surgical approach in combination with intravenous penicillin and metronidazol until clinical improvement is seen, followed by oral antibiotics for 2 - 4 weeks is generally efficient. es

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