Longitudinally extensive transverse myelitis with AQP4 antibodies revealing ovarian teratoma.
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Longitudinally extensive transverse myelitis with AQP4 antibodies revealing ovarian teratoma.

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Longitudinally extensive transverse myelitis with AQP4 antibodies revealing ovarian teratoma.

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dc.contributor.author Frasquet, M.
dc.contributor.author Bataller, L.
dc.contributor.author Torres-Vega, E.
dc.contributor.author Durán Moreno, María
dc.contributor.author García Verdugo, José Manuel
dc.contributor.author Sevilla, T.
dc.contributor.author Rivas, Salvador
dc.contributor.author Pérez-Miralles, F.
dc.contributor.author Simó-Castelló, M.
dc.contributor.author Casanova, B.
dc.date.accessioned 2014-01-20T08:50:11Z
dc.date.available 2014-01-20T08:50:11Z
dc.date.issued 2013
dc.identifier.uri http://dx.doi.org/10.1016/j.jneuroim.2013.07.003
dc.identifier.uri http://hdl.handle.net/10550/32388
dc.description.abstract Paraneoplastic myelitis is a rare inflammatory disorder most frequently associated with solid tumors or lymphoproliferative disorders. Patients often harbor onconeuronal antibodies and their prognosis is usually poor. Here we report a 42-year old woman with longitudinally extensive transverse myelitis and aquaporin-4 (AQP4) antibodies that led to the diagnosis of ovarian teratoma. After tumor removal and immune therapy (including corticosteroids, plasma exchange, intravenous immunoglobulins and rituximab) the patient progressively improved achieving complete recovery. Histological study of the teratoma demonstrated neural tissue containing AQP4 expressing cells and intense inflammatory infiltrates, providing evidence for a possible paraneoplastic link between both disorders.
dc.relation.ispartof Journal of Neuroimmunology, 2013, vol. 263, num. 1-2, p. 145-147
dc.rights.uri info:eu-repo/semantics/openAccess
dc.source Frasquet, M. Bataller, L. Torres-Vega, E. Durán Moreno, María García Verdugo, José Manuel Sevilla, T. Rivas, Salvador Pérez-Miralles, F. Simó-Castelló, M. Casanova, B. 2013 Longitudinally extensive transverse myelitis with AQP4 antibodies revealing ovarian teratoma. Journal of Neuroimmunology 263 1-2 145 147
dc.subject Neurociències
dc.subject Sistema nerviós Malalties
dc.title Longitudinally extensive transverse myelitis with AQP4 antibodies revealing ovarian teratoma.
dc.type info:eu-repo/semantics/article
dc.date.updated 2014-01-20T08:50:11Z
dc.identifier.doi http://dx.doi.org/10.1016/j.jneuroim.2013.07.003
dc.identifier.idgrec 093139

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