Yeast HAT1 and HAT2 deletions have different life-span and transcriptome phenotypes
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Yeast HAT1 and HAT2 deletions have different life-span and transcriptome phenotypes

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Yeast HAT1 and HAT2 deletions have different life-span and transcriptome phenotypes

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dc.contributor.author Rosaleny Peralvo, Lorena Estefanía
dc.contributor.author Antúnez Temporal, Oreto
dc.contributor.author Ruiz García, Ana Belén
dc.contributor.author Pérez Ortín, José Enrique
dc.contributor.author Tordera Donderis, Vicente
dc.date.accessioned 2013-12-04T12:37:41Z
dc.date.available 2013-12-04T12:37:41Z
dc.date.issued 2005
dc.identifier.uri http://hdl.handle.net/10550/32048
dc.description.abstract HAT-B is a yeast histone acetyltransferase composed of Hat1, Hat2 and Hif1 proteins. We demonstrate that a hat2 mutant or a hat1hat2 double mutant, but not a hat1 mutant, have an extended life-span. Transcriptome analysis shows that the single hat mutants are not very different from wild type. However, the comparison of the hat1 and hat2 transcriptomes shows that they are different. The hat1hat2 double mutant shows a transcriptional phenotype similar to that of the hat1 mutant but strongly enhanced. These results indicate that Hat2p could have additional functions in the cell to those of Hat1p.
dc.relation.ispartof Febs Letters, 2005, vol. 579, num. 19, p. 4063-4068
dc.rights.uri info:eu-repo/semantics/openAccess
dc.source Rosaleny Peralvo, Lorena Estefania Antúnez, O. Ruiz Garcia, Ana Belén Pérez Ortin, José Enrique Todera Donderis, Vicente 2005 Yeast HAT1 and HAT2 deletions have different life-span and transcriptome phenotypes Febs Letters 579 19 4063 4068
dc.subject RNA
dc.subject ADN
dc.title Yeast HAT1 and HAT2 deletions have different life-span and transcriptome phenotypes
dc.type info:eu-repo/semantics/article
dc.date.updated 2013-12-04T12:37:41Z
dc.identifier.idgrec 020447

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