Birth weight impacts on wave reflections in children and adolescents
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Birth weight impacts on wave reflections in children and adolescents

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Birth weight impacts on wave reflections in children and adolescents

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dc.contributor.author Lurbe i Ferrer, Empar
dc.contributor.author Torró Doménech, María Isabel
dc.contributor.author Carvajal Roca, María Eva
dc.contributor.author Alvarez, Vicente
dc.contributor.author Redón i Más, Josep
dc.date.accessioned 2011-08-19T09:04:59Z
dc.date.available 2011-08-19T09:04:59Z
dc.date.issued 2003
dc.identifier.uri http://hdl.handle.net/10550/20044
dc.description.abstract The objective of the present study was to assess central aortic pressure and wave reflection in children and adolescents at different birth weights. Two hundred nineteen healthy children (126 girls), from 7 to 18 years of age (mean, 11.3 years) and born at term after a normotensive pregnancy, were included. The subjects were divided according to birth weight: <2.5 kg, from 2.5 to 2.999 kg, from 3.0 to 3.5 kg, and >3.5 kg. Pressure waveforms were recorded from the radial artery of the wrist, and the waveform data were then processed by the SphygmoCor radial/aortic transform software module to produce the estimated aortic pressure waveform. Augmentation index, an estimate of the pulse wave reflection, was significantly higher in children with the lowest birth weights compared with the other birth weight groups. In a multiple regression analysis, short stature, low heart rate, female gender, and lower birth weight had independent significant inverse correlations to the augmentation index when adjusted for diastolic blood pressure (R^2=0.21). In summary, the results showed a relatively aged phenotype of large-vessel function in the children with the lowest birth weights. These early alterations may be amplified throughout life and may contribute to the increased cardiovascular risk associated with low birth weight. en
dc.language.iso en en
dc.relation http://hyper.ahajournals.org/cgi/reprint/41/3/646 en
dc.source LURBE FERRER, Maria Desamparados ; Torró Doménech, María Isabel; Carvajal, Eva ; Alvarez, Vicente ; Redon Mas, Josep, 2003, Birth Weight Impacts on Wave Reflections in Children and Adolescents, Hypertension, vol. 42, no. 3, p. 646-650 en
dc.subject Birth weight ; Augmentation index ; Children ; Pulse pressure en
dc.title Birth weight impacts on wave reflections in children and adolescents en
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS ::Medicina interna en
dc.identifier.doi 10.1161/01.HYP.0000048341.52293.7C en
dc.description.private Lurbe Ferrer, Maria Desamparados, Empar.Lurbe@uv.es ; Redon Mas, Josep, Josep.Redon@uv.es en
dc.identifier.idgrec 018532 en

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