Stereoselective synthesis of the published structure of synargentolide A and of one of its stereoisomers
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Stereoselective synthesis of the published structure of synargentolide A and of one of its stereoisomers

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Stereoselective synthesis of the published structure of synargentolide A and of one of its stereoisomers

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dc.contributor.author García-Fortanet, Jorge
dc.contributor.author Murga, Juan
dc.contributor.author Carda, Miguel
dc.contributor.author Marco Ventura, Juan Alberto
dc.date.accessioned 2010-06-08T10:26:28Z
dc.date.available 2010-06-08T10:26:28Z
dc.date.issued 2005
dc.identifier.uri http://hdl.handle.net/10550/12896
dc.description.abstract A stereoselective synthesis is described of the structure published for the naturally occurring synargentolide A, an α,β-unsaturated lactone. The key steps of the synthesis were a Brown´s asymmetric allylation and a ring closing metathesis. The spectroscopic data of the synthetic product were very close to those of the natural product but did not exactly match them. An epimer of the published structure was then synthesized according to a similar strategy. Again, the data of the synthetic product did not match those reported for the natural product. It is thus likely that the actual structure of synargentolide A differs from the published one in more than mere stereochemical aspects. en
dc.language.iso en en
dc.relation http://www.arkat-usa.org/get-file/19597/ en
dc.source GARCÍA-FORTANET, Jorge ; Murga, Juan ; Carda, Miguel ; Marco Ventura, Juan Alberto, 2005, Stereoselective synthesis of the published structure of synargentolide A and of one of its stereoisomers, Arkivoc, vol. 2005, no. IX, p. 175-188 en
dc.subject Synargentolide A ; Ring-closing metathesis ; Asymmetric allylboration ; Asymmetric dihydroxylation en
dc.title Stereoselective synthesis of the published structure of synargentolide A and of one of its stereoisomers en
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::QUÍMICA en
dc.subject.unesco UNESCO::QUÍMICA::Química orgánica en
dc.description.private Marco Ventura, Juan Alberto, alberto.marco@uv.es en
dc.identifier.idgrec 020768 en

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