Stereoselective synthesis of the published structure of synargentolide A and of one of its stereoisomers
NAGIOS: RODERIC FUNCIONANDO

Stereoselective synthesis of the published structure of synargentolide A and of one of its stereoisomers

DSpace Repository

Stereoselective synthesis of the published structure of synargentolide A and of one of its stereoisomers

Show full item record

View       (247.5Kb)

Exportar a Refworks
    
García-Fortanet, Jorge; Murga, Juan; Carda, Miguel; Marco Ventura, Juan Alberto
This document is a artículo publicadoDate2005
A stereoselective synthesis is described of the structure published for the naturally occurring synargentolide A, an α,β-unsaturated lactone. The key steps of the synthesis were a Brown´s asymmetric allylation and a ring closing metathesis. The spectroscopic data of the synthetic product were very close to those of the natural product but did not exactly match them. An epimer of the published structure was then synthesized according to a similar strategy. Again, the data of the synthetic product did not match those reported for the natural product. It is thus likely that the actual structure of synargentolide A differs from the published one in more than mere stereochemical aspects.

    GARCÍA-FORTANET, Jorge ; Murga, Juan ; Carda, Miguel ; Marco Ventura, Juan Alberto, 2005, Stereoselective synthesis of the published structure of synargentolide A and of one of its stereoisomers, Arkivoc, vol. 2005, no. IX, p. 175-188
http://www.arkat-usa.org/get-file/19597/
distribuido bajo licencia Creative Commons de Reconocimiento-NoComercial 3.0 No adaptada

This item appears in the following Collection(s)

Show full item record

Search DSpace

Advanced Search

Browse

Statistics